Physicochemical stability of pembrolizumab admixture solution in normal saline intravenous infusion bag

normal saline and dextrose-saline infusion comparison in the duration of active phase in nulliparous women

conclusions the administration of dextrose saline was associated with a shortened active phase and second stage of labor in vaginally delivered nulliparous women. results of 174 objects enrolled, 150 women delivered vaginally and completed the study. there was a significant difference in the duration of active phase between the groups (ns: 270.20 ± 13.37 minutes; d5ns: 206.67 ± 11.72 minutes) (...

A One-Man Apparatus for Intravenous Saline Infusion

Stability study of docetaxel solution (0.9%, saline) using Non-PVC and PVC tubes for intravenous administration

BACKGROUND Di-2-ethylhexyl phthalate (DEHP) are added to poly(vinyl chloride)(PVC) infusion tubes as a plasticizer to ensure tube flexibility. In addition to previously reported disadvantages of DEHP, released DEHP molecules from PVC tubes can easily interact with surfactants in anticancer drug solutions (i.e., polysorbate 80 for Taxotere®-Inj) and reduce the solubility of docetaxel in aqueous ...

Stability studies of lincomycin hydrochloride in aqueous solution and intravenous infusion fluids.

PURPOSE The purpose of this study was to evaluate the chemical stability of Lincocin(®) (lincomycin hydrochloride) in commonly used intravenous fluids at room temperature (25°C), at accelerated-degradation temperatures and in selected buffer solutions. MATERIALS AND METHODS The stability of Lincocin(®) injection (containing lincomycin 600 mg/2 mL as the hydrochloride) stored at 25°C±0.1°C in ...

Stability of meropenem in normal saline solution after storage at room temperature.

The bactericidal activity of meropenem is determined by the time that concentrations in tissue and serum are above the MIC for the pathogens during the dosing interval. Thus, the most effective mode of administering of meropenem is continuous infusion. However, the stability of meropenem reconstituted in solution is influenced by the storage temperature. Until now we have had no data to evaluat...